(2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester - Names and Identifiers
(2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester - Physico-chemical Properties
Molecular Formula | C14H22N2O2
|
Molar Mass | 250.34 |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
(2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester - Introduction
(2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester is an organic compound with the chemical formula C13H20N2O2. The following is an introduction to its nature, use, preparation and safety information:
Nature:
(2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester is a white solid, soluble in organic solvents such as ether and methanol. It has a melting point of 66-68°C and a boiling point of 318°C. It has a density of 1.0g/cm³.
Use:
(2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester plays an important role in drug research and application. It can be used as an intermediate in organic synthesis for the synthesis of biologically active compounds, such as drugs, pesticides or electrochemical materials. In addition, it can be used as an amino acid protecting group, a chiral reagent, and a precursor of an organic catalyst.
Method:
(2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester can be prepared by etherification. The specific preparation method is as follows:
First, 2-amino-3-phenylpropanol is reacted with tert-butyl formate in a suitable solvent to produce (2-amino-3-phenylpropyl)-carbamic acid methyl ester. Then, through acid-base neutralization reaction, (2-Amino-3-phenyl-propyl)-carbamic acid tert-butyl ester is obtained.
Safety Information:
(2-Amino-3-phenyl-propyl)-carbamic the security of acid tert-butyl ester is relatively high, the following matters still need to be paid attention:
1. During the operation, avoid contact with skin and eyes, and ensure that the operation is carried out in a well-ventilated area.
2. It has low toxicity, but it is still recommended to wear appropriate personal protective equipment, such as gloves, goggles and protective clothing.
3. It should be stored in a cool, dry place, away from fire and oxidant.
4. In handling and disposal, local rules and regulations should be followed to ensure safety.
Last Update:2024-04-09 21:01:54